By Gerhardus de Jong
This monograph deals the reader an entire evaluate on either ideas and functions of CE-MS. beginning with an introductory bankruptcy on detection in CE, additionally comparable and extra really good thoughts equivalent to electrophoretic and chromatographic preconcentration are mentioned. a different emphasis is wear CE-MS interfaces, that are defined intimately. In a separate bankruptcy, recognition is paid to sheath-liquid interfacing. The advancements and chances of microchip CE-MS also are defined. functions to all proper parts are mentioned in specified chapters, every one written by way of specialists within the respective fields.
along with purposes in pharmaceutical research and bioanalysis, contemporary implementations in foodstuff technology, forensic research, research of intact proteins, metabolomics and proteomics are highlighted. MS is a superbly acceptable detection procedure for CE, as effective separation is coupled to delicate and choice detection. in addition, MS promises constitution info at the separated compounds. CE-MS has now been built right into a robust hyphenated process complementary to LC-MS. This monograph is an designated resource of data for everybody facing and attracted to CE-MS
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This monograph bargains the reader an entire assessment on either rules and purposes of CE-MS. beginning with an introductory bankruptcy on detection in CE, additionally comparable and extra really good strategies similar to electrophoretic and chromatographic preconcentration are mentioned. a different emphasis is wear CE-MS interfaces, that are defined intimately.
Additional info for Capillary Electrophoresis - Mass Spectrometry (CE-MS) Principles and Applications
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Only one of these interfaces (CESI 8000, AB SCIEX) is commercialized and is therefore more widespread in use, yet there has been signiﬁcant growth in the ﬁeld of CE-MS. Future commercialization of other CE-MS interfaces would allow for more widespread use by giving options for choosing an interface best suited for the kind of analysis one plans to do. In time, interfaces such as those presented in this chapter may begin to replace the coaxial sheathliquid interface, which is still a standard interface used for many CE-MS applications.
Capillary Electrophoresis - Mass Spectrometry (CE-MS) Principles and Applications by Gerhardus de Jong