Download Adverse Drug Reactions by Michael Holt, Cynthia Ju (auth.), Jack Uetrecht (eds.) PDF

By Michael Holt, Cynthia Ju (auth.), Jack Uetrecht (eds.)

ISBN-10: 3642006620

ISBN-13: 9783642006623

This booklet offers the present kingdom of information of simple mechanisms of difficult drug reactions (ADRs). the main target is on idiosyncratic drug reactions simply because they're the main tough to accommodate. It begins with a normal description of the key pursuits for ADRs by way of an outline of what are almost immediately believed to be mediators and biochemical pathways excited about idiosyncratic drug reactions. there's additionally an outline of numerous examples of ADRs that serve to demonstrate particular elements of ADR mechanisms. finally the ebook indicates that finally greater equipment are had to expect which drug applicants tend to reason ADRs and which sufferers are at elevated possibility. yet at the moment examine appears to be like faraway from this goal.

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Extra resources for Adverse Drug Reactions

Sample text

30 T Cell Stimulation by Drugs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Stimulation of naı¨ve T Cells (Sensitization Phase) . . . . . . . . . . . . . . . . . . 2 Effector Phase in Immune-Mediated Drug Hypersensitivity . . . . . . . . . . . . . 34 3 Different Types of T Cell-Mediated Drug Hypersensitivity Reactions . . . . . . . . . . . 41 4 Clinical Features and Pathophysiology of Cutaneous Reactions .

30 T Cell Stimulation by Drugs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Stimulation of naı¨ve T Cells (Sensitization Phase) . . . . . . . . . . . . . . . . . . 2 Effector Phase in Immune-Mediated Drug Hypersensitivity . . . . . . . . . . . . . 34 3 Different Types of T Cell-Mediated Drug Hypersensitivity Reactions . . . . . . . . . .

The adverse effects of drugs and other chemicals on the liver, 2nd edn. Lippicott Williams & Wilkins, Philadelphia Zimmerman HJ, Lewis JH, Ishak KG, Maddrey WC (1984) Ticrynafen-associated hepatic injury: analysis of 340 cases. Hepatology 4:315–323 Drug Hypersensitivity Reactions Involving Skin Oliver Hausmann, Benno Schnyder, and Werner J. Pichler Contents 1 2 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 T Cell Stimulation by Drugs .

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Adverse Drug Reactions by Michael Holt, Cynthia Ju (auth.), Jack Uetrecht (eds.)


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